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Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil, another nondihydropyridine (non-DHP) calcium channel blocker.
Before taking Cardizem you should talk with your doctor if you have heart disease, congestive heart failure, irregular heart rhythm that slows down your heart rate (arrhythmia), sick sinus syndrome, liver or kidney disease, cirrhosis, low blood pressure, any allergies. The medication can increase liver enzymes which may be a sign of liver damage. This drug may make you dizzy. Do not drive or perform tasks that require alertness. Avoid drinking alcohol. Grapefruit and grapefruit juice may interact with diltiazem and lead to potentially dangerous effects.
Diltiazem is in a group of drugs called calcium channel blockers. It works by relaxing the muscles of your heart and blood vessels. Diltiazem is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.
In patients with hypertension or coronary heart disease, combination therapy with diltiazem and a beta-blocker usually enhances therapeutic benefit relative to monotherapy, but adverse effects attributable to this combination, especially in patients with left ventricular dysfunction or latent cardiac conduction ...
Take Cardizem exactly as prescribed by your doctor. The recommended dose can range from 30 mg to 360 mg daily which is usually taken 3 or 4 times a day. The recommended starting dose for treatment of chest pain (angina) is 30 mg four times daily (before meals and at bedtime). If necessary, your doctor may increase your dose to better control your chest pain. The dosage can also be decreased if you experience bothersome side effects.
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