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Schizophrenia is associated with an overactivity of dopamine in the brain, and this may be associated with the delusions and hallucinations that are a feature of this disease. Clozapine works by blocking the receptors in the brain that dopamine acts on.
A patient should try clozaril for at least four to six weeks. Some symptoms such as hallucinations, anxiety, paranoia, and bizarre behavior should improve within that time. Other symptoms may take longer. Additional improvements may be noticed over six to twelve months.
Clozapine can be taken with or without food. Take the regular oral tablet (Clozaril) with a full glass of water. The orally-disintegrating tablet (FazaClo) can be taken without water. Keep the tablet in its blister pack until you are ready to take it.
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