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Metabolism. Lithium is naturally found in all tissues. It is absorbed in the intestinal tract (small intestine) through the sodium channel, and is excreted through the kidneys. ... Lithium is the most important component which increases the concentration of this protein in the brain.
Lithium is used to treat and prevent episodes of mania in people with bipolar disorder (manic depressive disorder). Lithium is in a class of medications called antimanic agents, which work by decreasing abnormal activity in the brain.
Lamictal (lamotrigine) is an anti-epileptic medication, also called an anticonvulsant. Lamictal is used either alone or in combination with other medications to treat epileptic seizures in adults and children. Lamotrigine is also used to delay mood episodes in adults with bipolar disorder (manic depression).
Lithium affects the flow of sodium through nerve and muscle cells in the body. Sodium affects excitation or mania. Lithium is used to treat the manic episodes of manic depression. Manic symptoms include hyperactivity, rushed speech, poor judgment, reduced need for sleep, aggression, and anger.
Taking lithium with these medications used for depression might cause there to be too much serotonin. This could cause serious side effects including heart problems, shivering, and anxiety. ... Lithium can affect a brain chemical called serotonin.
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