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The average elimination half-life in individuals with normal renal function is 5 to 6 hr. Linear kinetic processes adequately describe the absorption and elimination of metoclopramide. Approximately 85% of the radioactivity of an orally administered dose appears in the urine within 72 hr.
"Maxeran is an antiemetic medication and dopamine antagonist. As a gastrointestinal motility agent, it is most often prescribed to patients with gastroparesis, a condition that often occurs in patients with diabetes. The drug works by increasing the rate at which the stomach and intestines move during digestion.
Take Maxolon exactly as prescribed by your doctor. Take this medication by mouth 30 minutes before meals and at bedtime, usually 4 times daily. Dosage is based on your weight, medical condition, and response to treatment. When taken for heartburn or reflux disease the drug is usually taken three times a day about 30 minutes before each meal. When used to treat nausea and vomiting, the medication may be given only once or when needed.
It works by increasing the movements or contractions of the stomach and intestines. It relieves symptoms such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite. Metoclopramide is also used to treat heartburn for patients with gastroesophageal reflux disease (GERD).
Reglan can also help people with diabetes who have a condition known as gastroparesis (poor emptying of the stomach). ... Reglan is in a class of drugs called prokinetic agents, which work by increasing muscle contractions in the upper digestive tract to speed up movement through the stomach and intestines.
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