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The mean serum half-lives of sulfamethoxazole and trimethoprim are 10 and 8 to 10 hours, respectively. However, patients with severely impaired renal function exhibit an increase in the half-lives of both components, requiring dosage regimen adjustment (see DOSAGE AND ADMINISTRATION section).
This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type).
BACTRIM (sulfamethoxazole and trimethoprim) is a synthetic antibacterial combination product available in DS (double strength) tablets, each containing 800 mg sulfamethoxazole and 160 mg trimethoprim; in tablets, each containing 400 mg sulfamethoxazole and 80 mg trimethoprim for oral administration.
Signs and symptoms of Bactrim overdose include: Anorexia. Fluctuating pain in the abdomen. Nausea and vomiting. Dizziness. Headache. Drowsiness. Unconsciousness. Fever.
Bactrim has an elimination half life of 6 to 12 hours. It usually takes around 5 to 6 half lives for a drug to be completely eliminated from your system. Other factors also affect elimination (age, health, weight, metabolism) but you can expect that your husband should be free of bactrim after about three days
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