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They are better known as nucleoside analogues or "nukes." When the HIV virus enters a healthy cell, it attempts to make copies of itself. It does this by using an enzyme called reverse transcriptase. The NRTIs work because they block that enzyme.
Non-nucleoside reverse-transcriptase inhibitors (NNRTIs) are antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV). NNRTIs inhibit reverse transcriptase (RT), an enzyme that controls the replication of the genetic material of HIV.
It's been one year since I have started taking the FDA approved pill called Truvada for HIV prevention. The only sanctioned medicine (aka PrEP or pre-exposure prophylaxis) that prevents HIV infection, Not even condoms are approved by the FDA to prevent HIV.
Nucleotide analogs are nucleotides which contain a nucleic acid analogue, a sugar and one to three phosphate groups. Nucleoside and nucleotide analogues can be used in therapeutic drugs, include a range of antiviral products used to prevent viral replication in infected cells.
Integrase inhibitors, also known as integrase strand transfer inhibitors (INSTIs), are a class of antiretroviral drug designed to block the action of integrase, a viral enzyme that inserts the viral genome into the DNA of the host cell.
Rilpivirine is a drug used as part of antiretroviral therapy (ART). It is also called Edurant. It is manufactured by Janssen Pharmaceuticals. Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (a “non-nuke” or NNRTI).
Less serious side effects may include: mild diarrhea. mild nausea or stomach pain; headache, dizziness, depressed mood; strange dreams; mild itching or skin rash; or. changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
Less serious side effects may include: mild diarrhea. mild nausea or stomach pain; headache, dizziness, depressed mood; strange dreams; mild itching or skin rash; or. changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
Development History and FDA Approval Process for Truvada Date Article Jul 16, 2012 FDA Approves Truvada for Reducing the Risk of Sexually Acquired HIV InfectionAug 2, 2004 Truvada Gilead Sciences, Inc. - Treatment for HIV Infection
Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication of HIV and other retroviruses
Entry inhibitors, also known as fusion inhibitors, are a class of antiretroviral drugs, used in combination therapy for the treatment of HIV infection. This class of drugs interferes with the binding, fusion and entry of an HIV virion to a human cell.
TRUVADA (emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg) is a type of medicine called a nucleoside analog reverse transcriptase inhibitor (NRTI) that is used to treat HIV-1 infection in people who weigh at least 77 lbs (35 kg).
TRUVADA® for PrEP (pre-exposure prophylaxis) is a prescription medicine that can be used to help reduce the risk of getting HIV-1 infection when used together with safer sex practices.
To cut the strings, HIV uses an enzyme called protease. Protease inhibitor drugs block the action of protease. They prevent the protease enzyme from cutting up the long HIV protein chain. By blocking protease, the drugs can interrupt the HIV life cycle and potentially stop the virus from copying itself.
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