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Crixivan belongs to a class of drugs known as protease inhibitors. It is used in combination with other HIV medications to treat the infection caused by the human immunodeficiency virus (HIV). HIV is the virus responsible for acquired immune deficiency syndrome (AIDS). Crixivan is not a cure for HIV. It does not prevent the spread of HIV to others through sexual contact or blood contamination. This medication may also be used to prevent HIV infection after contact with the virus.
Before taking Crixivan you should talk with your doctor if you have kidney stones, liver disease, liver failure, cirrhosis, hepatitis, diabetes, hemophilia, diabetes, heart problems, coronary artery disease, heart attack, kidney disease, kidney failure, any allergies. Children may be more sensitive to the side effects of this drug. Taking indinavir will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Avoid taking this medication with a meal high in calories, fat, and protein since this may decrease its effect.
Do not take Crixivan if you are allergic to indinavir or any ingredients of this medication, are taking any of the following medications: alprazolam, amiodarone, astemizole, cisapride, ergot derivatives (ergotamine, dihydroergotamine), midazolam, pimozide, terfenadine, triazolam. Let your doctor know if you are pregnant or breastfeeding.
Crixivan is used to help treat HIV infection by blocking the action of protease, an enzyme which the virus needs to multiply.
Tell your doctor about all other medications you use, especially: seizure medications (phenytoin, felbamate, carbamazepine), HIV/AIDS medications (nevirapine, lamivudine, ritonavir, zidovudine), phosphodiesterase type-5 inhibitors (tadalafil, sildenafil, vardenafil), insulin, heart rhythm medications (quinidine, flecainide, amiodarone), cyclosporine, tacrolimus, cholesterol-lowering medicines (fluvastatin, cerivastatin, simvastatin, lovastatin), calcium channel blockers (nimodipine, verapamil, nifedipine), antidepressants (fluoxetine, amitriptyline, citalopram, nortriptyline, doxepin), antibiotics (telithromycin, erythromycin, clarithromycin), fluticasone. Interaction between two medications does not always mean that you must stop taking one of them. Tell your doctor or prescriber about all prescription, over-the-counter, and herbal medications you are taking.
Take Crixivan exactly as prescribed by your doctor. Take this medication by mouth with a full glass of water. The recommended adult dose is 800 mg taken with water every 8 hours. In people with mild to moderate liver disease, the recommended dose is 600 mg every eight hours. It should be taken one hour before or 2 hours after a meal. To help decrease the risk of kidney stones, drink at least 6 full glasses of water or other liquids throughout the day.
Get emergency medical help if you have stomach pain, nausea, vomiting, heartburn, loss of appetite, headache, dizziness, sleepiness, weakness, confusion, dehydration, mouth sores, muscle aches or pain, pounding heartbeat, increased thirst, increased urination, yellowing of the skin or eyes, weight loss, painful urination, blood in urine, dark urine, pale stools, chest pain or pressure, peeling, blistering, back pain, chills, fever, rash, itching, swelling of the face, tongue, throat, trouble breathing. If you notice other effects not listed above, contact your doctor.
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