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Possible side effects of chloramphenicol: All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Mild diarrhea, nausea, or vomiting.
Chloramphenicol is used to treat bacterial eye infections. It is also used to treat serious life-threatening bacterial infections such as typhoid fever when given orally or intravenously. It is an antibiotic, sometimes known as a broad spectrum antibiotic as is effective against a wide variety of bacteria.
Chloramphenicol is a bacteriostatic by inhibiting protein synthesis. It prevents protein chain elongation by inhibiting the peptidyl transferase activity of the bacterial ribosome. It specifically binds to A2451 and A2452 residues in the 23S rRNA of the 50S ribosomal subunit, preventing peptide bond formation.
Common side effects of chloramphenicol sodium succinate include: diarrhea. nausea. vomiting. mouth pain. headache. altered mental status. confusion. fever.
Chloramphenicol eye drops and eye ointment are used to treat bacterial eye infections. Eye infections are a common cause of conjunctivitis. In conjunctivitis, your eye becomes inflamed, feels gritty, and may water more than usual.
Chemical class Examples Mode of actionTetracyclines Tetracycline Inhibit translation (protein synthesis)Semisynthetic tetracycline Doxycycline Inhibit translation (protein synthesis)
BRAND NAME: Chloromycetin, Econochlor, Ocu-Chlor (These are discontinued brands in the US) DRUG CLASS AND MECHANISM: Chloramphenicol is a man-made antibiotic. It slows growth of bacteria by preventing them from producing important proteins that they need to survive.
Chloramphenicol Chloramphenicol Inhibits translation (protein synthesis)Quinolones Nalidixic acid Inhibits DNA replication
Chloramphenicol is bactericidal at clinically achievable concentrations against Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis. It is bacteriostatic against gram-negative bacilli of the family Enterobacteriaceae and against Staphylococcus aureus.
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