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Indomethacin works by reducing hormones that cause inflammation and pain in the body. Indomethacin is used to treat pain or inflammation caused by many conditions such as arthritis, gout, ankylosing spondylitis, bursitis, or tendinitis.
Carbonic Anhydrase inhibitors cause acidosis by preventing bicarb reabsorption. They cause hypokalemia by increasing the tubular flow, thereby maintaining a K+ excretion gradient and minimizing the ability to reabsorb it. ... Hyperkalemia is caused by the potassium-sparing diuretics.
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