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This medication is also used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen (Nolvadex). Anastrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen the body makes.
Anastrozole (Arimidex), exemestane (Aromasin) and letrozole (Femara) are known as aromatase inhibitors and all work in similar ways to each other. This means they share many of the same side effects, although there are some differences.
Common side effects of Arimidex include constipation, diarrhea, nausea, vomiting, upset stomach, loss of appetite, body aches and pains (back pain, bone pain, joint pain or stiffness), breast swelling/tenderness/pain, headache, dry mouth, scratchy or sore throat, increased cough, dizziness, trouble sleeping (insomnia), ...
Anastrozole has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism. It can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer.
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