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Clozapine can be taken with or without food. Take the regular oral tablet (Clozaril) with a full glass of water. The orally-disintegrating tablet (FazaClo) can be taken without water. Keep the tablet in its blister pack until you are ready to take it.
Clozaril (clozapine) is an antipsychotic medication. It works by changing the actions of chemicals in the brain. Clozaril is used to treat severe schizophrenia, or to reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.
Common clozapine side effects may include:**weight gain;**tremor, dizziness, spinning sensation;**headache, drowsiness;**fast heart rate;**nausea, constipation;**dry mouth, or increased salivation;**blurred vision; or.**increased sweating.
Schizophrenia is associated with an overactivity of dopamine in the brain, and this may be associated with the delusions and hallucinations that are a feature of this disease. Clozapine works by blocking the receptors in the brain that dopamine acts on.
Clozapine is classified as an atypical antipsychotic drug because it binds to serotonin as well as dopamine receptors. Clozapine is a partial agonist at the 5-HT1A subunit of the serotonin receptor, putatively improving depression, anxiety, and the negative cognitive symptoms associated with schizophrenia.
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