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Both medications can increase the chance that the patient may have bleeding issues. Therefore the potential that Plavix and ibuprofen (And other NSAIDs) taken together can increase the risk of severe bleeding to dangerous levels means that these two drugs should usually not be taken together.
It takes 5.5 x half-lifes of a medicine for it to be out of one's system. So Plavix should be cleared from your system in about 5.5 x 6 hours = 33 hours.
Elimination. Following an oral dose of 14C-labeled clopidogrel in humans, approximately 50% of total radioactivity was excreted in urine and approximately 46% in feces over the 5 days post-dosing. After a single, oral dose of 75 mg, clopidogrel has a half-life of approximately 6 hours.
Do not change your dose or stop taking Plavix without talking to your doctor first. Stopping Plavix may increase your risk of heart attack or stroke. Take Plavix with aspirin as instructed by your doctor. ... Do not take 2 doses of Plavix at the same time unless your doctor tells you to.
USES: Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease).It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open
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