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Before taking Copegus you should talk with your doctor if you have kidney or liver disease, hepatitis B infection, blood cell disorder, cancer, psoriasis, diabetes, sarcoidosis, thyroid disorder, human immunodeficiency virus (HIV or AIDS), heart disease, high blood pressure, or a heart attack, pancreatitis, diabetes, depression or suicide attempt, drug or alcohol addiction, liver or other organ transplant. This drug may make you dizzy or unusually tired or cause blurred vision. Do not drive or perform tasks that require alertness. Avoid alcoholic beverages. Alcohol can increase the risk of damage to your liver. Elderly people may be at greater risk for anemia while using this drug.
Copegus is an antiviral drug. It is used in combination with interferon for the treatment of chronic hepatitis C. Copegus monotherapy is not effective for the treatment of chronic hepatitis C virus infection and should not be used alone for this indication. It works by helping the immune system fight the hepatitis C virus, and by making it harder for the virus to reproduce within the body.
It is therefore necessary to consider an earlier reduction in the ribavirin dose in such patients to prevent discontinuation of treatment because of anemia. ... However, because red blood cells lack dephosphorylation enzymes, ribavirin accumulates in cells and destroys the cells, causing hemolytic anemia.
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