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Carbonic anhydrase inhibitors cause increased excretion of bicarbonate with accompanying sodium, potassium and water, resulting in an increased flow of alkaline urine. They inhibit transport of bicarbonate into the interstitium from the proximal convoluted tubule.
The half-life of acetazolamide is between 10 to 15 hours. As an estimate it usually takes around 5 to 6 half lives for a drug to be eliminated from your system.
Studies have shown that prophylactic administration of acetazolamide at a dose of 250mg every eight to twelve hours before and during rapid ascent to altitude results in fewer and/or less severe symptoms (such as headache, nausea, shortness of breath, dizziness, drowsiness, and fatigue) of acute mountain sickness (AMS) ...
Tell your doctor if you have ever had an allergic reaction to a sulfa-based drug such as sulfamethoxazole (e.g., Bactrim, Septra, Gantanol). Acetazolamide is also a sulfa-based drug, and you may have a similar reaction to it.
4) Diamox also can cause some stomach pain, nausea and loss of appetite. People often lose 10 pounds when they first go on it. It's best to take it with a meal. The weight-loss effect doesn't last or it would be sold as a weight-loss drug
Indomethacin works by reducing hormones that cause inflammation and pain in the body. Indomethacin is used to treat pain or inflammation caused by many conditions such as arthritis, gout, ankylosing spondylitis, bursitis, or tendinitis.
Treating certain types of glaucoma, epilepsy, or edema (fluid buildup) in combination with other medicines. It is also used to treat or prevent symptoms of mountain sickness. It may also be used for other conditions as determined by your doctor. Acetazolamide is a carbonic anhydrase inhibitor.
BRAND NAME: Bumex (discontinued brand) DRUG CLASS AND MECHANISM: Bumetanide is a potent diuretic (water pill) that causes a profound increase in urine output (diuresis) by preventing the kidney from retaining fluid.
Carbonic Anhydrase inhibitors cause acidosis by preventing bicarb reabsorption. They cause hypokalemia by increasing the tubular flow, thereby maintaining a K+ excretion gradient and minimizing the ability to reabsorb it. ... Hyperkalemia is caused by the potassium-sparing diuretics.
Treating certain types of glaucoma in combination with other medicines. It is also used to treat or prevent symptoms of mountain sickness. It may also be used for other conditions as determined by your doctor. Diamox Sequels sustained-release capsules are a carbonic anhydrase inhibitor.
Other side effects of Diamox Sequels include blurred vision or changes in vision, dry mouth, drowsiness, loss of appetite, stomach upset, nausea, vomiting, constipation, diarrhea, changes in taste, headache, tiredness, drowsiness, fatigue, weakness, nervousness, mild tremor, confusion, increased sensitivity of the skin ...
This drug is also used with other medications to treat a certain type of eye problem (open-angle glaucoma). Acetazolamide is a "water pill" (diuretic). It decreases the amount of fluid that can build up in the eye.
Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as antiglaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders, or osteoporosis.
Methazolamide is a carbonic anhydrase inhibitor. Carbonic anhydrase is a protein in the body. Methazolamide reduces the activity of this protein. Methazolamide is used to treat glaucoma.
In other words if you took a dose at 9am Monday, it would take somewhere between 50 to 90 hours (2 to 4 days) for the dose to be eliminated from your system.
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