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Approved in the US for use in 1995, it is a non-steroidal aromatase inhibiting drug (acronym AI) and is approved for treatment of breast cancer after surgery and for metastasis in women. Since breast cancer can be heightened by the increase in estrogen, arimidex is used to inhibit the synthesis of estrogen
Arimidex (anastrozole) is what is classified as an aromatase inhibitor. It's original designed use was to treat breast cancer in women by lowering estrogen. It was eventually discovered that arimidex could benefit bodybuilders by blocking estrogen formation or lowering already existing levels.
Eighty-five percent of radiolabeled anastrozole was recovered in feces and urine. Hepatic metabolism accounts for approximately 85% of anastrozole elimination. Renal elimination accounts for approximately 10% of total clearance. The mean elimination half-life of anastrozole is 50 hours.
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