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When your LES (lower esophageal sphincter) relaxes, excess acids can flow up, or reflux, into your esophagus. This can create the painful sensation of heartburn. Prilosec OTC works by directly blocking many of the active stomach pumps that produce acid before they start. Prilosec OTC is a proton pump inhibitor (PPI).
Esomeprazole acts in the stomach to decrease the production of stomach acid. Proton pumps are found on cells that line the stomach and are used by these cells to produce stomach acid. Esomeprazole works by inhibiting the action of the proton pumps, and this reduces the production of stomach acid.
Nexium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
To treat too much acid in the stomach caused by a growth in the pancreas (Zollinger-Ellison syndrome): The recommended dose is Nexium 40 mg twice a day. Your doctor will adjust the dose depending on your needs and will also decide how long you need to take the medicine for. The maximum dose is 80 mg twice a day.
Take each dose with a full glass (8 ounces) of water. Esomeprazole should be taken at least one hour before a meal. Do not crush, chew, break, or open a delayed-release capsule. Swallow it whole.
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