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Oxymorphone (brand names Opana, Numorphan, Numorphone), also known as 14-hydroxydihydromorphinone, is a powerful semi-synthetic opioid analgesic (painkiller) first developed in Germany in 1914, patented in the USA by Endo Pharmaceuticals in 1955 and introduced to the United States market in January 1959 and other ...
Opana (oxymorphone) is an opioid pain medication. An opioid is sometimes called a narcotic. Opana is used to treat moderate to severe pain. The extended-release form of this medicine is for around-the-clock treatment of severe pain.
Oxycodone is metabolized in part by cytochrome P450 2D6 to oxymorphone, which represents less than 15% of the total administered dose.6 However, oxymorphone has a significantly longer half life (7-9 hours)7 than does oxycodone, whose mean elimination half-life following a single, oral dose is 3.51 ± 1.43 hours.
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The tablet strength describes the amount of oxymorphone hydrochloride per tablet. The tablets contain the following inactive ingredients: hypromellose, iron oxide black, methylparaben, propylene glycol, silicified microcrystalline cellulose, sodium stearyl fumarate, TIMERx® -N, titanium dioxide, and triacetin.