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    Less serious metoclopramide side effects may include: feeling restless, drowsy, tired, or dizzy; headache, sleep problems (insomnia); nausea, vomiting, diarrhea; breast tenderness or swelling; changes in your menstrual periods; or. urinating more than usual.
    Metoclopramide is also used to relieve symptoms caused by slow stomach emptying in people who have diabetes. These symptoms include nausea, vomiting, heartburn, loss of appetite, and feeling of fullness that lasts long after meals. Metoclopramide is in a class of medications called prokinetic agents.
    "Maxeran is an antiemetic medication and dopamine antagonist. As a gastrointestinal motility agent, it is most often prescribed to patients with gastroparesis, a condition that often occurs in patients with diabetes. The drug works by increasing the rate at which the stomach and intestines move during digestion.
    Metoclopramide increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines. Metoclopramide is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms.
    The risk of this side effect is higher in women, diabetics, and older adults. Take metoclopramide 30 minutes before eating. Metoclopramide is usually taken before meals and at bedtime. Your doctor may want you to take the medication as needed only with meals that usually cause heartburn.
    Metoclopramide is used to relieve heartburn caused by gastroesophageal reflux disease (GERD). It's also used to treat symptoms of diabetic gastroparesis. (This is slow stomach emptying in people with diabetes). Symptoms include nausea, vomiting, heartburn, constantly feeling full after meals, and loss of appetite.
    Reglan can also help people with diabetes who have a condition known as gastroparesis (poor emptying of the stomach). ... Reglan is in a class of drugs called prokinetic agents, which work by increasing muscle contractions in the upper digestive tract to speed up movement through the stomach and intestines.
    This medication is used to treat certain conditions of the stomach and intestines. ... Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/abdominal fullness. Metoclopramide works by blocking a natural substance (dopamine). It speeds up stomach emptying and movement of the upper intestines.
    REGLAN SP 10 (Reglan 10 mg) Generic Name: metoclopramide. Pill imprint REGLAN SP 10 has been identified as Reglan 10 mg. Reglan is used in the treatment of nausea/vomiting; gastroparesis; migraine; lactation augmentation; gerd (and more), and belongs to the drug classes GI stimulants, miscellaneous antiemetics.
    Reglan Overview - Patient Information: Side Effects. Drowsiness, dizziness, tiredness, trouble sleeping, agitation, headache, and diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
    The average elimination half-life in individuals with normal renal function is 5 to 6 hr. Linear kinetic processes adequately describe the absorption and elimination of metoclopramide. Approximately 85% of the radioactivity of an orally administered dose appears in the urine within 72 hr.
    Reglan (metoclopramide) increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines. Reglan is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms.
    The antiemetic action of metoclopramide is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone in the central nervous system — this action prevents nausea and vomiting triggered by most stimuli. At higher doses, 5-HT3 antagonist activity may also contribute to the antiemetic effect.
    It works by increasing the movements or contractions of the stomach and intestines. It relieves symptoms such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite. Metoclopramide is also used to treat heartburn for patients with gastroesophageal reflux disease (GERD).
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