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Maxolon is used to treat heartburn, gastric reflux disease and gastroparesis and to prevent nausea or vomiting from chemotherapy.
Metoclopramide is also used to relieve symptoms caused by slow stomach emptying in people who have diabetes. These symptoms include nausea, vomiting, heartburn, loss of appetite, and feeling of fullness that lasts long after meals. Metoclopramide is in a class of medications called prokinetic agents.
"Maxeran is an antiemetic medication and dopamine antagonist. As a gastrointestinal motility agent, it is most often prescribed to patients with gastroparesis, a condition that often occurs in patients with diabetes. The drug works by increasing the rate at which the stomach and intestines move during digestion.
Metoclopramide increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines. Metoclopramide is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms.
The average elimination half-life in individuals with normal renal function is 5 to 6 hr. Linear kinetic processes adequately describe the absorption and elimination of metoclopramide. Approximately 85% of the radioactivity of an orally administered dose appears in the urine within 72 hr.
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