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Nexium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
To treat too much acid in the stomach caused by a growth in the pancreas (Zollinger-Ellison syndrome): The recommended dose is Nexium 40 mg twice a day. Your doctor will adjust the dose depending on your needs and will also decide how long you need to take the medicine for. The maximum dose is 80 mg twice a day.
Nexium is a proton pump inhibitor. It decreases the overall acidity in the stomach by shutting down some of the proton pumps. It is not an "anti-acid." Antacids work by coating the stomach and lowering the acidity of the stomach contents, due to their strong base properties.
When your LES (lower esophageal sphincter) relaxes, excess acids can flow up, or reflux, into your esophagus. This can create the painful sensation of heartburn. Prilosec OTC works by directly blocking many of the active stomach pumps that produce acid before they start. Prilosec OTC is a proton pump inhibitor (PPI).
The only active ingredient in Nexium is the exact same thing as the only active ingredient in omeprazole (Prilosec), a (now) generic drug made by the same company, which is over the counter and four to eight times cheaper.
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