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Consequently there is particular interest in topiramate (Topamax and generic), a drug approved to treat certain types of seizures and prevent migraine headaches, but is used off-label to control binging and purging, and to promote weight loss in people with eating disorders.
As I said, phentermine is an appetite suppressant. It is thought to trigger the release of the chemical norepinephrine in the brain, which increases blood concentrations of leptin, an appetite-regulating hormone. Topiramate, commonly known as Topamax, is prescribed as an anticonvulsant and migraine medication.
Qsymia is a federally controlled substance (CIV) because it contains phentermine and can be abused or lead to drug dependence. Keep Qsymia in a safe place, to protect it from theft. Never give your Qsymia to anyone else, because it may cause death or harm them.
For oral dosage form (extended-release capsules): For weight loss: Adults—At first, one tablet of 3.75 milligrams (mg) of phentermine and 23 mg of topiramate once a day for 14 days. After 14 days, your doctor may increase your dose to 7.5 mg of phentermine and 46 mg of topiramate once a day.
Qsymia 7.5 mg/46 mg (phentermine 7.5 mg and topiramate 46 mg extended-release) capsules; Qsymia 11.25 mg/69 mg (phentermine 11.25 mg and topiramate 69 mg extended-release) capsules; Qsymia 15 mg/92 mg (phentermine 15 mg and topiramate 92 mg extended-release) capsules.
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