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    Accutane Overview - Patient Information: Side Effects. SIDE EFFECTS: Dry lips and mouth, minor swelling of the eyelids or lips, crusty skin, nosebleeds, upset stomach, or thinning of hair may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
    While taking Accutane, it is important not to drink alcohol, or to only drink alcohol in extreme moderation. This is because Accutane can potentially have some side effects related to liver toxicity, and combining it with alcohol could make you at greater risk of these toxic side effects.
    Accutane is linked to serious side effects like birth defects, thoughts of suicide, depression and bowel disorders. ... Although the drug was hailed by dermatologists as a breakthrough treatment for patients with severe acne, Accutane's dangerous side effects affected thousands of patients during the past 30 years
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    The recommended dosage range for Accutane is 0.5 to 1.0 mg/kg/day given in two divided doses with food for 15 to 20 weeks. In studies comparing 0.1, 0.5, and 1.0 mg/kg/day,8 it was found that all dosages provided initial clearing of disease, but there was a greater need for retreatment with the lower dosages.
    Isotretinoin (13-cis retinoic acid) is a vitamin-A derivative (retinoid). The liver naturally makes small quantities of isotretinoin from vitamin-A, but the drug we prescribe is made synthetically. Isotretinoin was developed in the 1950s, but only started being used in the mid 1970s.
    Isotretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly. Isotretinoin is used to treat severe nodular acne that has not responded to other treatments, including antibiotics.
    Dry skin and eyes Muscle aches
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    A standard course of therapy is 16 to 20 weeks. At the end of 16 weeks, about 85% of patients are clear. The beneficial effects of Accutane do not stop when the drug is discontinued. A further reduction of acne lesions and improvement of scarring is seen for months after treatment has stopped.
    Isotretinoin belongs to a group of medicines known as retinoids, which are substances related to vitamin A. It is used to treat acne which is severe, or which has not got better with other treatments such as oral antibiotics or skin treatments
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    The bad news is that if it isn't used correctly there can be serious side effects. Accutane can cause severe birth defects. ... Note, Accutane is NOT anabolic steroids, and should not be considered in the same drug category. It's an anti-acne medication.
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    Always take isotretinoin with a full glass of water to prevent the capsule from melting in your esophagus (food pipe), causing irritation. Do not chew or suck on the capsule. Swallow it as quickly as possible. Take this medication for the entire length of time prescribed by your doctor.
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