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Atorvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Atorvastatin and ezetimibe is a combination medicine that reduces blood levels of "bad" cholesterol, such as low-density lipoprotein (LDL), apolipoprotein-B (apo-B), triglycerides, or non-high-density lipoprotein (non-HDL).
EZETROL works by decreasing the absorption of cholesterol in the small intestine. Statins lower cholesterol in a different way, by reducing the amount of cholesterol made in the liver. EZETROL adds to the cholesterol-lowering effect of statins. Your doctor may have prescribed EZETROL for another reason.
It is associated with muscle cramps, stiffness and spasms. Rhabdomyolysis is serious because it can cause the breakdown of muscles, which can cause acute kidney failure and can ultimately be fatal. Patients who develop unexplained muscle pain while taking Zetia should consult with their doctor immediately.
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Both ezetimibe and ezetimibe-glucuronide are eliminated from plasma with a half-life of approximately 22 hours for both ezetimibe and ezetimibeglucuronide. Plasma concentration-time profiles exhibit multiple peaks, suggesting enterohepatic recycling.
It is associated with muscle cramps, stiffness and spasms. Rhabdomyolysis is serious because it can cause the breakdown of muscles, which can cause acute kidney failure and can ultimately be fatal. Patients who develop unexplained muscle pain while taking Zetia should consult with their doctor immediately.
