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Oxycodone is metabolized in part by cytochrome P450 2D6 to oxymorphone, which represents less than 15% of the total administered dose.6 However, oxymorphone has a significantly longer half life (7-9 hours)7 than does oxycodone, whose mean elimination half-life following a single, oral dose is 3.51 ± 1.43 hours.
Opana is a powerful narcotic painkiller, classified by the government as a Schedule II Controlled Substance. ... Oxymorphone is more toxic than the natural opioid morphine, but less toxic than the fully synthetic ones like methadone.
The tablet strength describes the amount of oxymorphone hydrochloride per tablet. The tablets contain the following inactive ingredients: hypromellose, iron oxide black, methylparaben, propylene glycol, silicified microcrystalline cellulose, sodium stearyl fumarate, TIMERx® -N, titanium dioxide, and triacetin.
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