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A gonadotropin-releasing hormone agonist (GnRH agonist, GnRH–A) is a synthetic peptide modeled after the hypothalamic neurohormone GnRH that interacts with the gonadotropin-releasing hormone receptor to elicit its biologic response, the release of the pituitary hormones FSH and LH.
The most common form of hormonal treatment for prostate cancer is luteinizing hormone-releasing hormone (LHRH)-agonist therapy. During the first 1 to 3 weeks of LHRH-agonist therapy, an initial increase in testosterone is associated with a condition known as “flare.”
Flutamide is an antiandrogen. It works in the body to prevent the actions of androgens (male hormones). Flutamide is used together with another hormone to treat prostate cancer. Flutamide may also be used for purposes not listed in this medication guide.
Cyproterone acetate/Ethinylestradiol works by preventing the production of and blocking the effects of the hormone testosterone. Cyproterone acetate/Ethinylestradiol is used to treat acne and hirsutism in women. It is only used to treat acne when previous treatments have not been successful.
Faslodex (fulvestrant) is an anti-estrogen medication. It works by blocking the actions of estrogen in the body. Certain types of breast cancer use estrogen to grow and multiply in the body. Faslodex is used to treat some hormone-related breast cancer.
In rare cases, flutamide has caused severe liver damage resulting in death or hospitalization. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, "flu-like" symptoms, yellow skin or eyes, itching, clay-colored stools, or dark urine.
Dutasteride is a 5 alpha-reductase enzyme inhibitor. It works by lowering levels of a hormone called dihydrotestosterone (DHT), which is a major cause of prostate growth. Lowering DHT leads to shrinkage of the enlarged prostate gland.
Femara (generic name is letrozole) is an oral drug which can be an effective fertility treatment for women with ovulation problems, or for those with unexplained infertility. This medication is in a class of drug called aromatase inhibitors. Femara has mainly been used to treat certain cases of breast cancer.
Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow. Tamoxifen is used to treat some types of breast cancer in men and women.
Zoladex (goserelin) is a man-made form of a hormone that regulates many processes in the body. Goserelin overstimulates the body's own production of certain hormones, which causes that production to shut down temporarily. Zoladex is used in men to treat symptoms of prostate cancer.
Abiraterone acetate (INN, USAN, BAN, JAN) (brand names Zytiga, Abiratas, Abretone, Abirapro) is a steroidal antiandrogen, specifically an androgen synthesis inhibitor, used in combination with prednisone in metastatic castration-resistant prostate cancer (formerly hormone-resistant or hormone-refractory prostate cancer ...
Etidronate is used to treat a certain type of bone disease called Paget's disease. This disease weakens and deforms bones. Etidronate works by slowing bone loss, helping to keep your bones strong and less likely to break. It also helps reduce bone pain from this disease.
Casodex (bicalutamide) is an anti-androgen. It works in the body by preventing the actions of androgens (male hormones). Casodex is used together with another hormone to treat prostate cancer. Casodex may also be used for purposes not listed in this medication guide.
Ketoconazole is an antifungal medication that fights infections caused by fungus. Ketoconazole is not for use in treated fungal infections of the fingernails or toenails. This medicine is also not for use in treating prostate cancer or Cushing syndrome.
Lupron (leuprolide) overstimulates the body's own production of certain hormones, which causes that production to shut down temporarily. Leuprolide reduces the amount of testosterone in men or estrogen in women. Lupron is used in men to treat the symptoms of prostate cancer.
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