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Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication of HIV and other retroviruses
TRUVADA (emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg) is a type of medicine called a nucleoside analog reverse transcriptase inhibitor (NRTI) that is used to treat HIV-1 infection in people who weigh at least 77 lbs (35 kg).
Less serious side effects may include: mild diarrhea. mild nausea or stomach pain; headache, dizziness, depressed mood; strange dreams; mild itching or skin rash; or. changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
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Integrase inhibitors, also known as integrase strand transfer inhibitors (INSTIs), are a class of antiretroviral drug designed to block the action of integrase, a viral enzyme that inserts the viral genome into the DNA of the host cell.