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Time to peak plasma concentration is approximately one hour. Distribution – Although the plasma half life of spironolactone itself is short (1.3 hours) the half lives of the active metabolites are longer (ranging from 2.8 to 11.2 hours). Spironolactone is estimated to be 90% protein bound.
Answer: No, Spironolactone is not a statin. Spironolactone is a diuretic and a high blood pressure medication. Spironolactone is a diuretic and a high blood pressure medication.
Spironolactone tablets belong to a group of medicines called potassium-sparing diuretics (water tablets), which help you lose excess fluid from your body. They may be used for: congestive heart failure. nephrotic syndrome (a kidney disorder)
The pump acts to re-absorb sodium and water in exchange for potassium, which is then eliminated in the urine. Consequently, aldosterone antagonism can cause hyperkalemia. Hyperkalemia is an established adverse effect of both spironolactone and eplerenone. The symptoms of hyperkalemia begin with muscle weakness.























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