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Like the SGAs, antidepressants trazodone, mianserine, nefazodone and mirtazapine are also inhibitors at 5HT2 receptors. They are, however, lacking D2 receptor affinity and, thus, antipsychotic efficacy.
Some people had been prescribed mirtazapine, a presynaptic alpha 2 adrenoreceptor antagonist unrelated to SSRIs or SNRIs. It is thought that this medicine acts on receptors in the brain, increasing the amounts of the chemical messengers noradrenaline and serotonin and can improve mood.
Remeron is one brand name for mirtazapine, an antidepressant and alpha-2 antagonist. It is a tetracyclic antidepressant and is different from selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs).
Mirtazapine is a newer antidepressant that exhibits both noradrenergic and serotonergic activity. It is at least as effective as the older antidepressants for treating mild to severe depression. Sedation is the most common side effect. ... Mirtazapine is relatively safe in overdose.
Most Frequently Prescribed Psychotropic Drugs Xanax (alprazolam), 48.5 million. Zoloft (sertraline), 41.4 million. Celexa (citalopram), 39.4 million. Prozac (fluoxetine), 28.3 million. Ativan (lorazepam), 27.9 million. Desyrel (trazodone HCL), 26.2 million. Lexapro (escitalopram), 24.9 million.
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