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The authors also found that metformin was well tolerated, though hypoglycemia was a concern. Already, metformin is being used outside of diabetes. Polycystic ovary syndrome (PCOS) is a hormonal disorder in women that is linked to insulin resistance and type 2 diabetes.
We start metformin at 500 mg once daily, increase to 500 mg twice a day after one week, then to 500 mg 3 times daily after another week. If the 3 times daily dose cannot be tolerated due to side effects, we remain on the twice-daily dose. The most effective dose of Glucophage for PCOS is generally 500mg 3 times daily.
Januvia helps lower blood sugar in two ways. It helps the body increase insulin to stabilize blood sugar and decrease sugars that are made in the liver. It is a part of the class of diabetes medications called DPP-4 inhibitors. DPP-4 is a protein made by the body that plays a role in glucose metabolism.D
Metformin is a quick-acting oral medication—you will typically see some effect within 48 hours of starting the medication. Maximum effect will take about four to five days, but that depends on the dose.
When your BG is running so high sometimes the body is eating up fat, muscle, or whatever is in its path to get nutrients pretty much. And that isnt a healthy loss. I've never heard of metformin causing weight gain. Like someone else mentioned, some people lose weight on it.
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