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Integrase inhibitors, also known as integrase strand transfer inhibitors (INSTIs), are a class of antiretroviral drug designed to block the action of integrase, a viral enzyme that inserts the viral genome into the DNA of the host cell.
Rilpivirine is a drug used as part of antiretroviral therapy (ART). It is also called Edurant. It is manufactured by Janssen Pharmaceuticals. Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (a “non-nuke” or NNRTI).
TRUVADA® for PrEP (pre-exposure prophylaxis) is a prescription medicine that can be used to help reduce the risk of getting HIV-1 infection when used together with safer sex practices.
Nucleotide analogs are nucleotides which contain a nucleic acid analogue, a sugar and one to three phosphate groups. Nucleoside and nucleotide analogues can be used in therapeutic drugs, include a range of antiviral products used to prevent viral replication in infected cells.
TRUVADA (emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg) is a type of medicine called a nucleoside analog reverse transcriptase inhibitor (NRTI) that is used to treat HIV-1 infection in people who weigh at least 77 lbs (35 kg).
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