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Clozaril (clozapine) is an antipsychotic medication. It works by changing the actions of chemicals in the brain. Clozaril is used to treat severe schizophrenia, or to reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.
It is also known as a second generation antipsychotic (SGA) or atypical antipsychotic. Clozapine rebalances dopamine and serotonin to improve thinking, mood, and behavior. Symptoms of schizophrenia include: Hallucinations - imagined voices or images that seem real.
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Metabolism And Excretion. Clozapine is almost completely metabolized prior to excretion, and only trace amounts of unchanged drug are detected in the urine and feces. Clozapine is a substrate for many cytochrome P450 isozymes, in particular CYP1A2, CYP2D6, and CYP3A4.
Common clozapine side effects may include:**weight gain;**tremor, dizziness, spinning sensation;**headache, drowsiness;**fast heart rate;**nausea, constipation;**dry mouth, or increased salivation;**blurred vision; or.**increased sweating.
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