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If you think you have overdosed the medicine seek emergency medical help at once. The overdose symptoms are extremely low blood pressure, kidney failure, increased heart rate, high potassium in the blood (hyperkalemia), dizziness, lightheadedness, fainting, decreased urine output, drowsiness, headache, back pain, slow pulse, irregular heartbeat, loss of consciousness.
Before taking Lotrel you should talk with your doctor if you have heart disease, congestive heart failure or aortic stenosis, liver or kidney disease, cirrhosis, diabetes, scleroderma, systemic lupus erythematosus, angioedema, any allergies. Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects. Lotrel may impair your thinking or reactions. Do not drive or perform tasks that require alertness.
Tell your doctor about all other medications you use, especially: potassium-containing products (potassium gluconate, salt substitutes, potassium chloride), potassium-sparing diuretics (triamterene, amiloride, spironolactone), simvastatin, nonsteroidal anti-inflammatory drugs (diclofenac, ibuprofen, celecoxib, ketoprofen, oxaprozin), diuretics (furosemide, torsemide, bumetanide), antacids, lithium. Interaction between two medications does not always mean that you must stop taking one of them. Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking.
Lotrel is a combination of two medicines: benazepril hydrochloride and amlodipine besylate. Benazepril is part of a class of drugs called angiotensin-converting enzyme inhibitors. It helps to block the angiotensin-converting enzyme, which is normally a part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, Benazepril causes blood vessels to relax. Amlodipine is part of a class of drugs called calcium channel blockers. It helps to slow down the rate at which calcium moves into your blood vessel walls and makes it easier for the heart to pump blood. Lotrel is used to treat high blood pressure (hypertension). It is usually given after other blood pressure medications have been tried without successful treatment.
Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Benazepril also widens blood vessels and also prevents the body from retaining water. Amlodipine and benazepril is a combination medicine used to treat high blood pressure (hypertension).
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