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Take Copegus exactly as prescribed by your doctor. Ribavirin is not effective when used alone to treat hepatitis C. It must be used together with an interferon alfa product (such as Peg-Intron or Intron A) to treat chronic hepatitis C. Take this medication by mouth, usually twice daily with food for 24 to 48 weeks. Swallow this medication whole. The daily dose is 800 mg to 1200 mg administered orally in two divided doses. The recommended dose for hepatitis C in HCV/HIV coinfected patients is 800 mg daily for a total of 48 weeks, regardless of genotype.
The treatment begins with pegylated interferon and ribavirin for the first four weeks, then Victrelis is added. The weekly cost of Victrelis is $1,100, according to Specialty Pharmacy News, meaning a 24-week treatment would cost approximately $22,000; a 48-week treatment would cost $48,400.
Less serious side effects may include: headache; muscle pain; dry mouth; nausea; vomiting, stomach pain, loss of appetite; weight loss; feeling tired or irritable; anxiety, mood changes; or.pain, swelling, or irritation where the interferon injection was given.
In addition, Ribavirin has a multiple dose half-life of 12 days, and it may persist in non-plasma compartments for as long as 6 months. Therefore, Ribavirin, including Ribavirin tablets, is contraindicated in women who are pregnant and in the male partners of women who are pregnant.
In general, the generic preparations are less expensive than the brand drugs. As a rough estimate, a 12-week course of generic ribavirin is in the range of $550 to $850. Accordingly, the ribavirin component of a 48-week treatment course costs approximately $1100 to $1700.
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